Immune modulation01
ATA2
- Modality
- DNA aptamer
- Target / direction
- TLR9 activation
- Research focus
- Immune activation
In vitro validation
Pipeline
Our therapeutic research pipeline
Candidates in innate immune signaling modulation and regenerative peptide therapeutics, described by the experimental evidence currently supporting each program.
DiscoveryCandidate identification and initial evaluation
In vitro validationBiological activity assessed in laboratory systems
Animal proof of conceptBiological effect observed in an animal model
9 research programs
Evidence labels describe experiments obtained; they do not indicate completion of studies required to begin clinical development.
Immune modulation02
ETI41 / ETI60
- Modality
- Small molecules
- Target / direction
- Endosomal TLR3/7/9 inhibition
- Research focus
- Autoimmune inflammation
In vitro · Animal PoC at program level
Immune modulation03
MyDIP2-4
- Modality
- Inhibitory peptide
- Target / direction
- MyD88-dependent signaling
- Research focus
- Psoriasis-like inflammation
Animal proof of concept
Immune modulation04
NIM5 Series
- Modality
- Small molecules
- Target / direction
- NLRP3 inhibition
- Research focus
- Neuroinflammation
Animal PoC at series level
Immune modulation05
ETA53
- Modality
- Small molecule
- Target / direction
- TLR9 inhibition
- Research focus
- Post-MI inflammation & remodeling
Animal proof of concept
Regenerative peptide06
FAP1
- Modality
- FGF-mimetic peptide
- Target / direction
- FGFR activation
- Research focus
- Diabetic wound repair
Animal proof of concept
Regenerative peptide07
VMP3
- Modality
- VEGF-mimetic peptide
- Target / direction
- VEGFR2 activation
- Research focus
- Angiogenesis & wound repair
Animal proof of concept
Regenerative peptide08
SDP-4
- Modality
- SDF-1α-mimetic peptide
- Target / direction
- CXCR4-related recruitment
- Research focus
- Tissue repair
Animal PoC for tissue repair
Regenerative peptide09
SP1
- Modality
- Substance P analog
- Target / direction
- NK1R-related recruitment
- Research focus
- Wound healing & regeneration
Animal PoC for tissue repair
Evidence interpretation
Program- or series-level findings are distinguished from evidence for an individual candidate. Tissue repair findings for SDP-4 and SP1 are considered separately from proof of endogenous recruitment in each study.